Function and Biology Details
Reaction catalysed:
L-erythro-7,8-dihydrobiopterin + NADP(+) = sepiapterin + NADPH
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Sepiapterin reductase (preferred)
PDBe Complex ID:
PDB-CPX-152880 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sepiapterin reductase
Molecule details ›
Chains: A, B, C, D
Length: 275 amino acids
Theoretical weight: 29.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain
Length: 275 amino acids
Theoretical weight: 29.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P35270 (Residues: 1-261; Coverage: 100%)
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain
