› 4xzv

X-ray diffraction
3.58Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129076 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Maltose/maltodextrin-binding periplasmic protein; TP53-regulated inhibitor of apoptosis 1 Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 446 amino acids
Theoretical weight: 48.94 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
  • Canonical: O43715 (Residues: 2-76; Coverage: 99%)
Gene names: 15E1.1, HSPC132, JW3994, TRIAP1, b4034, malE
Sequence domains:
PRELI domain containing protein 3A Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 186 amino acids
Theoretical weight: 20.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96N28 (Residues: 1-172; Coverage: 100%)
Gene names: C18orf43, PRELID3A, SLMO1
Sequence domains: PRELI-like family

Ligands and Environments

Carbohydrate polymer : NEW Components: GLC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P1
Unit cell:
a: 79.62Å b: 80.68Å c: 98.02Å
α: 87.25° β: 85.62° γ: 89.92°
R-values:
R R work R free
0.275 0.273 0.309
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Type 2 diabetes mellitus, oxidative stress and inflammation: examining the links.
Oguntibeju OO. (2019)
17 more

3 mentions without citation

Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes.
Miliara et al. (2015)
2 more