› 4y1u

X-ray diffraction
1.76Å resolution

Complex of human Galectin-1 and Galbeta1-4GlcNAc

Released:
DOI: 10.2210/pdb4y1u/pdb
PDB entry 4y1u coloured by chain, front view.
PDB entry 4y1u coloured by chain, side view.
PDB entry 4y1u coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lin HY, Hsieh TJ, Lin CH

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140624 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 154 amino acids
Theoretical weight: 16.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAG, GAL
Carbohydrate polymer
No bound ligands
1 modified residue:
Ligand CSO 10 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13C1
Spacegroup: P212121
Unit cell:
a: 43.3Å b: 58.234Å c: 111.649Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.182 0.227
Expression system: Escherichia coli BL21(DE3)

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