› 4y22

X-ray diffraction
2.5Å resolution

Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc

Released:
DOI: 10.2210/pdb4y22/pdb
PDB entry 4y22 coloured by chain, front view.
PDB entry 4y22 coloured by chain, side view.
PDB entry 4y22 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Lin HY, Hsieh TJ, Lin CH

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140623 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Galectin-1 Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 16.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls
Galectin-1 Chain: B
Molecule details ›
Chain: B
Length: 154 amino acids
Theoretical weight: 16.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P09382 (Residues: 3-135; Coverage: 99%)
Gene name: LGALS1
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MAG, SGA
Carbohydrate polymer
No bound ligands
1 modified residue:
Ligand CSO 4 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13C1
Spacegroup: P212121
Unit cell:
a: 44.41Å b: 58.184Å c: 112.763Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.23 0.278
Expression system: Escherichia coli BL21(DE3)

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