› 4yeq

X-ray diffraction
3.2Å resolution

L4b Domain of Human Laminin alpha-2

Released:
DOI: 10.2210/pdb4yeq/pdb
PDB entry 4yeq coloured by chain, front view.
PDB entry 4yeq coloured by chain, side view.
PDB entry 4yeq coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Laminin L4 domain structure resembles adhesion modules in ephrin receptor and other transmembrane glycoproteins.
Moran T, Gat Y, Fass D
FEBS J 282 2746-57 (2015)
PMID: 25962468

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Laminin subunit alpha-2 Chain: U
Molecule details ›
Chain: U
Length: 203 amino acids
Theoretical weight: 23.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P24043 (Residues: 1177-1379; Coverage: 7%)
Gene names: LAMA2, LAMM
Sequence domains: Laminin B (Domain IV)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A, RIGAKU RUH3R
Spacegroup: P6322
Unit cell:
a: 161.107Å b: 161.107Å c: 78.929Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.212 0.279
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Structural biology of laminins.
Hohenester E. (2019)
7 other articles

6 mentions without citation

Assessment of template-based modeling of protein structure in CASP11.
Modi et al. (2016)
5 more