› 4yi0

X-ray diffraction
1.81Å resolution

Structure of mouse importin a1 bound to Pom121NLS

Released:
DOI: 10.2210/pdb4yi0/pdb
PDB entry 4yi0 coloured by chain, front view.
PDB entry 4yi0 coloured by chain, side view.
PDB entry 4yi0 coloured by chain, top view.
Source organisms:
Entry authors: Lokareddy RK, Cingolani G

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156501 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha-1 Chain: C
Molecule details ›
Chain: C
Length: 460 amino acids
Theoretical weight: 49.89 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P52293 (Residues: 70-529; Coverage: 87%)
Gene names: Kpna2, Rch1
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Nuclear envelope pore membrane protein POM 121 Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.64 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P52591 (Residues: 291-320; Coverage: 3%)
Gene names: Nup121, Pom121

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P212121
Unit cell:
a: 78.337Å b: 89.753Å c: 97.868Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.182 0.21
Expression system: Escherichia coli

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