Function and Biology Details
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158907 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
Molecule details ›
Chain: A
Length: 405 amino acids
Theoretical weight: 45.64 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: RhoGEF domain
Structure domains:
Length: 405 amino acids
Theoretical weight: 45.64 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
Q8TCU6 (Residues: 1-404; Coverage: 24%)
Sequence domains: RhoGEF domain
Structure domains:
Ras-related C3 botulinum toxin substrate 1
Molecule details ›
Chain: B
Length: 179 amino acids
Theoretical weight: 19.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Length: 179 amino acids
Theoretical weight: 19.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P63000 (Residues: 1-177; Coverage: 92%)
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup:
C2221
Expression systems:
- Spodoptera frugiperda
- Escherichia coli
