› 4z18

X-ray diffraction
1.95Å resolution

CRYSTAL STRUCTURE OF HUMAN PD-L1

Released:
DOI: 10.2210/pdb4z18/pdb
PDB entry 4z18 coloured by chain, front view.
PDB entry 4z18 coloured by chain, side view.
PDB entry 4z18 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Fedorov AA, Fedorov EV, Samantha D, Hillerich B, Seidel RD, Almo SC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192784 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Programmed cell death 1 ligand 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 25.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q9NZQ7 (Residues: 19-239; Coverage: 81%)
Gene names: B7H1, CD274, PDCD1L1, PDCD1LG1, PDL1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: C2221
Unit cell:
a: 72.03Å b: 91.48Å c: 135.735Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.21 0.246
Expression system: Escherichia coli K-12

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