Function and Biology Details
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-124851 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DDB1- and CUL4-associated factor 1
Molecule details ›
Chains: A, D
Length: 349 amino acids
Theoretical weight: 39.78 KDa
Source organism: Homo sapiens
Expression system: Baculoviridae
UniProt:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Length: 349 amino acids
Theoretical weight: 39.78 KDa
Source organism: Homo sapiens
Expression system: Baculoviridae
UniProt:
- Canonical:
Q9Y4B6 (Residues: 1057-1396; Coverage: 23%)
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
Protein Vpr
Molecule details ›
Chains: B, E
Length: 100 amino acids
Theoretical weight: 12.2 KDa
Source organism: Simian immunodeficiency virus
Expression system: Escherichia coli
UniProt:
Sequence domains: VPR/VPX protein
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 100 amino acids
Theoretical weight: 12.2 KDa
Source organism: Simian immunodeficiency virus
Expression system: Escherichia coli
UniProt:
- Canonical: Q7ZB17 (Residues: 1-89; Coverage: 90%)
Sequence domains: VPR/VPX protein
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Molecule details ›
Chains: C, F
Length: 118 amino acids
Theoretical weight: 13.2 KDa
Source organism: Mandrillus sphinx
Expression system: Escherichia coli
UniProt:
Sequence domains: SAM domain (Sterile alpha motif)
Length: 118 amino acids
Theoretical weight: 13.2 KDa
Source organism: Mandrillus sphinx
Expression system: Escherichia coli
UniProt:
- Canonical: H6WEA4 (Residues: 1-115; Coverage: 18%)
Sequence domains: SAM domain (Sterile alpha motif)
