Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Complement C3b complex and Complement factor H (preferred)
PDBe Complex ID:
PDB-CPX-133841 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Complement C3d fragment
Molecule details ›
Chains: A, B, C
Length: 317 amino acids
Theoretical weight: 35.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: A-macroglobulin TED domain
Structure domains: Glycosyltransferase
Length: 317 amino acids
Theoretical weight: 35.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01024 (Residues: 996-1303; Coverage: 19%)
Sequence domains: A-macroglobulin TED domain
Structure domains: Glycosyltransferase
Complement factor H
Molecule details ›
Chains: D, E, F
Length: 129 amino acids
Theoretical weight: 14.77 KDa
Source organism: Homo sapiens
Expression system: Pichia
UniProt:
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Length: 129 amino acids
Theoretical weight: 14.77 KDa
Source organism: Homo sapiens
Expression system: Pichia
UniProt:
- Canonical: P08603 (Residues: 1107-1231; Coverage: 10%)
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1
Ligands and Environments
1 bound ligand:
No modified residues
Experiments and Validation Details
X-ray source:
SLS BEAMLINE X06DA
Spacegroup:
P1
Expression systems:
- Escherichia coli
- Pichia
