› 4zmt

X-ray diffraction
2.7Å resolution

Crystal structure of human P-cadherin (ss-X-dimer-long)

Released:
DOI: 10.2210/pdb4zmt/pdb
PDB entry 4zmt coloured by chain, front view.
PDB entry 4zmt coloured by chain, side view.
PDB entry 4zmt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism.
Kudo S, Caaveiro JM, Tsumoto K
Structure 24 1523-36 (2016)
PMID: 27545624

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149555 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin-3 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 232 amino acids
Theoretical weight: 25.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22223 (Residues: 108-338; Coverage: 29%)
Gene names: CDH3, CDHP
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

1 bound ligand:
Ligand CA 18 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P21
Unit cell:
a: 85.21Å b: 105.83Å c: 90.21Å
α: 90° β: 96.8° γ: 90°
R-values:
R R work R free
0.229 0.228 0.249
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.
Mège et al. (2017)
1 more