Function and Biology Details
Reaction catalysed:
(1a) [protein]-N(6)-acetyl-L-lysine + NAD(+) = [protein]-N(6)-(1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl)-L-lysine + nicotinamide
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-138125 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SirtT1 75 kDa fragment
Molecule details ›
Chain: A
Length: 356 amino acids
Theoretical weight: 40.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Sir2 family
Structure domains:
Length: 356 amino acids
Theoretical weight: 40.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q96EB6 (Residues: 183-505; Coverage: 43%)
Sequence domains: Sir2 family
Structure domains:
Cellular tumor antigen p53
Molecule details ›
Chain: B
Length: 7 amino acids
Theoretical weight: 986 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 7 amino acids
Theoretical weight: 986 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P04637 (Residues: 379-385; Coverage: 2%)
