Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134113 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Glycoprotein hormones alpha chain
Molecule details ›
Chains: A, D, G
Length: 92 amino acids
Theoretical weight: 10.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Glycoprotein hormone
Structure domains: Cystine-knot cytokines
Length: 92 amino acids
Theoretical weight: 10.18 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P01215 (Residues: 25-116; Coverage: 100%)
Sequence domains: Glycoprotein hormone
Structure domains: Cystine-knot cytokines
Follitropin subunit beta
Molecule details ›
Chains: B, E, H
Length: 111 amino acids
Theoretical weight: 12.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Cystine-knot domain
Structure domains: Cystine-knot cytokines
Length: 111 amino acids
Theoretical weight: 12.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P01225 (Residues: 19-129; Coverage: 100%)
Sequence domains: Cystine-knot domain
Structure domains: Cystine-knot cytokines
Follicle-stimulating hormone receptor
Molecule details ›
Chains: X, Y, Z
Length: 350 amino acids
Theoretical weight: 40.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 350 amino acids
Theoretical weight: 40.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P23945 (Residues: 17-366; Coverage: 52%)
Sequence domains:
- Leucine rich repeat N-terminal domain
- BspA type Leucine rich repeat region (6 copies)
- Gonadotropin hormone receptor transmembrane region
