› 4br6

X-ray diffraction
2Å resolution

Crystal structure of Chaetomium thermophilum MnSOD

Released:
DOI: 10.2210/pdb4br6/pdb
PDB entry 4br6 coloured by chain, front view.
PDB entry 4br6 coloured by chain, side view.
PDB entry 4br6 coloured by chain, top view.
Source organism: Chaetomium thermophilum
Primary publication:
Crystal structure and biochemical characterization of a manganese superoxide dismutase from Chaetomium thermophilum.
Haikarainen T, Frioux C, Zhnag LQ, Li DC, Papageorgiou AC
Biochim Biophys Acta 1844 422-9 (2014)
PMID: 24316252

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123736 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 197 amino acids
Theoretical weight: 21.86 KDa
Source organism: Chaetomium thermophilum
UniProt:
  • Canonical: F8V325 (Residues: 31-227; Coverage: 87%)
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand MN3 4 x MN3
Ligand NA 6 x NA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X13
Spacegroup: P61
Unit cell:
a: 69.14Å b: 69.14Å c: 300.43Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.123 0.12 0.178

Quick links

Citations

2 review citations

Stress response physiology of thermophiles.
Ranawat et al. (2017)
1 more

1 mention without citation

Parallel Molecular Evolution of Catalases and Superoxide Dismutases-Focus on Thermophilic Fungal Genomes.
Chovanová et al. (2020)