4bsx

X-ray diffraction
2.23Å resolution

Crystal Structure of the N terminal domain of TRIF (TIR-domain- containing adapter-inducing interferon-beta)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-184848 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TIR domain-containing adapter molecule 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 156 amino acids
Theoretical weight: 17.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8IUC6 (Residues: 1-153; Coverage: 22%)
Gene names: PRVTIRB, TICAM1, TRIF
Sequence domains: TRIF N-terminal domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P1
Unit cell:
a: 47.307Å b: 49.331Å c: 70.142Å
α: 88.66° β: 77.63° γ: 72.22°
R-values:
R R work R free
0.194 0.191 0.239
Expression system: Escherichia coli BL21(DE3)