Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 300-mer (preferred)
Assembly name:
VP1 (preferred)
PDBe Complex ID:
PDB-CPX-109080 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
VP1
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 32.83 KDa
Source organism: Enterovirus A71
UniProt:
Length: 298 amino acids
Theoretical weight: 32.83 KDa
Source organism: Enterovirus A71
UniProt:
- Canonical:
A9X4C2 (Residues: 566-863; Coverage: 14%)
VP2
Molecule details ›
Chain: B
Length: 254 amino acids
Theoretical weight: 27.8 KDa
Source organism: Enterovirus A71
UniProt:
Length: 254 amino acids
Theoretical weight: 27.8 KDa
Source organism: Enterovirus A71
UniProt:
- Canonical: A9X4C2 (Residues: 70-323; Coverage: 12%)
VP3
Molecule details ›
Chain: C
Length: 242 amino acids
Theoretical weight: 26.52 KDa
Source organism: Enterovirus A71
UniProt:
Length: 242 amino acids
Theoretical weight: 26.52 KDa
Source organism: Enterovirus A71
UniProt:
- Canonical: A9X4C2 (Residues: 324-565; Coverage: 11%)
