› 4ckh

Electron Microscopy
14Å resolution

Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy

Released:
DOI: 10.2210/pdb4ckh/pdb
PDB entry 4ckh coloured by chain, front view.
PDB entry 4ckh coloured by chain, side view.
PDB entry 4ckh coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A PH domain in ACAP1 possesses key features of the BAR domain in promoting membrane curvature.
Pang X, Fan J, Zhang Y, Zhang K, Gao B, Ma J, Li J, Deng Y, Zhou Q, Egelman EH, Hsu VW, Sun F
Dev Cell 31 73-86 (2014)
PMID: 25284369
Related structures: EMD-2547

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 40-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172167 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 382 amino acids
Theoretical weight: 43.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15027 (Residues: 1-377; Coverage: 51%)
Gene names: ACAP1, CENTB1, KIAA0050
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 14Å
Relevant EMDB volumes: EMD-2547
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

To degrade or not to degrade: mechanisms and significance of endocytic recycling.
Cullen et al. (2018)
2 more

1 mention without citation

A PH domain in ACAP1 possesses key features of the BAR domain in promoting membrane curvature.
Pang et al. (2014)