› 4csr

X-ray diffraction
1.5Å resolution

High resolution crystal structure of the histone fold dimer (NF-YB)-(NF-YC)

Released:
DOI: 10.2210/pdb4csr/pdb
PDB entry 4csr coloured by chain, front view.
PDB entry 4csr coloured by chain, side view.
PDB entry 4csr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Gnesutta N, Cocolo S, Mantovani R, Bolognesi M, Nardini M

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150405 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Nuclear transcription factor Y subunit beta Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25208 (Residues: 51-143; Coverage: 45%)
Gene names: HAP3, NFYB
Sequence domains: Histone-like transcription factor (CBF/NF-Y) and archaeal histone
Structure domains: Histone, subunit A
Nuclear transcription factor Y subunit gamma Chain: B
Molecule details ›
Chain: B
Length: 94 amino acids
Theoretical weight: 11.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13952 (Residues: 27-120; Coverage: 21%)
Gene name: NFYC
Sequence domains: Core histone H2A/H2B/H3/H4
Structure domains: Histone, subunit A

Ligands and Environments

1 bound ligand:
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P212121
Unit cell:
a: 51.67Å b: 60.8Å c: 61.61Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 0.145 0.184
Expression system: Escherichia coli

Quick links