› 4d9s

X-ray diffraction
1.7Å resolution

Crystal structure of Arabidopsis thaliana UVR8 (UV Resistance locus 8)

Released:
DOI: 10.2210/pdb4d9s/pdb
PDB entry 4d9s coloured by chain, front view.
PDB entry 4d9s coloured by chain, side view.
PDB entry 4d9s coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Plant UVR8 photoreceptor senses UV-B by tryptophan-mediated disruption of cross-dimer salt bridges.
Christie JM, Arvai AS, Baxter KJ, Heilmann M, Pratt AJ, O'Hara A, Kelly SM, Hothorn M, Smith BO, Hitomi K, Jenkins GI, Getzoff ED
Science 335 1492-6 (2012)
PMID: 22323738

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190355 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ultraviolet-B receptor UVR8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 406 amino acids
Theoretical weight: 43.55 KDa
Source organism: Arabidopsis thaliana
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9FN03 (Residues: 1-405; Coverage: 92%)
Gene names: At5g63860, MGI19.7, UVR8
Sequence domains: Regulator of chromosome condensation (RCC1) repeat
Structure domains: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P21
Unit cell:
a: 68.117Å b: 51.511Å c: 97.084Å
α: 90° β: 102.89° γ: 90°
R-values:
R R work R free
0.16 0.16 0.194
Expression system: Escherichia coli

Quick links

Citations

64 review citations

Light-controlled flavonoid biosynthesis in fruits.
Zoratti et al. (2014)
63 more

8 mentions without citation

How Does Photoreceptor UVR8 Perceive a UV-B Signal?
Yang et al. (2015)
7 more