› 4e59

X-ray diffraction
1.54Å resolution

Crystal structure of GCCGCCGC duplex

Released:
DOI: 10.2210/pdb4e59/pdb
PDB entry 4e59 coloured by chain, front view.
PDB entry 4e59 coloured by chain, side view.
PDB entry 4e59 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystallographic characterization of CCG repeats.
Kiliszek A, Kierzek R, Krzyzosiak WJ, Rypniewski W
Nucleic Acids Res 40 8155-62 (2012)
PMID: 22718980

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo hexamer
Assembly name:
PDBe Complex ID:
PDB-CPX-196794 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA duplex containing CCG repeats Chains: A, B
Molecule details ›
Chains: A, B
Length: 8 nucleotides
Theoretical weight: 2.52 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: R3
Unit cell:
a: 40.58Å b: 40.58Å c: 56.144Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.257 0.255 0.304
Expression system: Not provided

Quick links

Citations

4 review citations

Repeat associated non-ATG (RAN) translation: new starts in microsatellite expansion disorders.
Cleary et al. (2014)
3 more

6 mentions without citation

Structural studies of CNG repeats.
Kiliszek et al. (2014)
5 more