PDB 4elv structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

Biochemical function:

DNA-directed DNA polymerase activity

Biological process:

DNA repair

Cellular component:

not assigned

Sequence domains:

Structure analysis Details

Assembly composition:

hetero trimer (preferred)

Assembly name:

DNA polymerase I, thermostable and DNA (preferred)

PDBe Complex ID:

PDB-CPX-117425 (preferred)

Entry contents:

1 distinct polypeptide molecule
2 distinct DNA molecules

Macromolecules (3 distinct):

DNA polymerase I, thermostable Chain: A

Molecule details ›

Chain: A
Length: 540 amino acids
Theoretical weight: 60.94 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli
UniProt:

Canonical: P19821 (Residues: 293-832; Coverage: 65%)

Gene names: pol1, polA
Sequence domains:

Structure domains:

DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(0R8))-3') Chain: B

Molecule details ›

Chain: B
Length: 12 nucleotides
Theoretical weight: 3.74 KDa
Source organism: synthetic construct
Expression system: Not provided

DNA (5'-D(*AP*AP*AP*GP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3') Chain: C

Molecule details ›

Chain: C
Length: 16 nucleotides
Theoretical weight: 4.96 KDa
Source organism: synthetic construct
Expression system: Not provided