Function and Biology Details
Reaction catalysed:
(1a) S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [HECT-type E3 ubiquitin transferase]-L-cysteine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + S-ubiquitinyl-[HECT-type E3 ubiquitin transferase]-L-cysteine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136587 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Maltose/maltodextrin-binding periplasmic protein; Ubiquitin-protein ligase E3A
Molecule details ›
Chains: A, B
Length: 382 amino acids
Theoretical weight: 41.67 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II
Length: 382 amino acids
Theoretical weight: 41.67 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
- Canonical:
P0AEX9 (Residues: 27-392; Coverage: 99%) - Canonical: Q05086 (Residues: 400-417; Coverage: 2%)
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II
Protein E6
Molecule details ›
Chains: C, D
Length: 142 amino acids
Theoretical weight: 17.14 KDa
Source organism: Human papillomavirus 16
Expression system: Escherichia coli
UniProt:
Sequence domains: Early Protein (E6)
Structure domains: E6 early regulatory protein
Length: 142 amino acids
Theoretical weight: 17.14 KDa
Source organism: Human papillomavirus 16
Expression system: Escherichia coli
UniProt:
- Canonical: P03126 (Residues: 9-150; Coverage: 90%)
Sequence domains: Early Protein (E6)
Structure domains: E6 early regulatory protein
