› 4gjh

X-ray diffraction
2.8Å resolution

Crystal Structure of the TRAF domain of TRAF5

Released:
DOI: 10.2210/pdb4gjh/pdb
PDB entry 4gjh coloured by chain, front view.
PDB entry 4gjh coloured by chain, side view.
PDB entry 4gjh coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5.
Zhang P, Reichardt A, Liang H, Aliyari R, Cheng D, Wang Y, Xu F, Cheng G, Liu Y
Sci Signal 5 ra81 (2012)
PMID: 23150880

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159709 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TNF receptor-associated factor 5 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 178 amino acids
Theoretical weight: 20.37 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P70191 (Residues: 381-558; Coverage: 32%)
Gene name: Traf5
Sequence domains: TRAF/meprin, MATH domain
Structure domains: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-5A
Spacegroup: P212121
Unit cell:
a: 71.052Å b: 90.579Å c: 117.216Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.224 0.273
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Structure of TRAF Family: Current Understanding of Receptor Recognition.
Park HH. (2018)
2 more

6 mentions without citation

Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5.
Zhang et al. (2012)
5 more