› 4hae

X-ray diffraction
2Å resolution

Crystal structure of the CDYL2-chromodomain

Released:
DOI: 10.2210/pdb4hae/pdb
PDB entry 4hae coloured by chain, front view.
PDB entry 4hae coloured by chain, side view.
PDB entry 4hae coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Qin S, Dombrovski L, Tempel W, Dong A, Xu C, Bountra C, Arrowsmith CH, Edwards AM, Min J, Wu H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185443 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromodomain Y-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 81 amino acids
Theoretical weight: 9.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8N8U2 (Residues: 2-64; Coverage: 13%)
Gene name: CDYL2
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

2 bound ligands:
Ligand SO4 1 x SO4
Ligand UNX 7 x UNX
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6122
Unit cell:
a: 60.358Å b: 60.358Å c: 89.896Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.216 0.251
Expression system: Escherichia coli BL21(DE3)

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