› 4hbq

X-ray diffraction
1.4Å resolution

Crystal structure of a loop deleted mutant of Human MAdCAM-1 D1D2

Released:
DOI: 10.2210/pdb4hbq/pdb
PDB entry 4hbq coloured by chain, front view.
PDB entry 4hbq coloured by chain, side view.
PDB entry 4hbq coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Springer T, Yu Y, Zhu J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171710 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mucosal addressin cell adhesion molecule 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 206 amino acids
Theoretical weight: 21.7 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q13477 (Residues: 23-171, 180-224; Coverage: 53%)
Gene name: MADCAM1
Sequence domains: Adhesion molecule, immunoglobulin-like
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
Ligand SO4 2 x SO4
Ligand GOL 1 x GOL
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 58.32Å b: 69.7Å c: 101.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.144 0.143 0.178
Expression system: Homo sapiens

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