› 4heh

X-ray diffraction
2.05Å resolution

Crystal structure of AppA SCHIC domain from Rb. sphaeroides

Released:
DOI: 10.2210/pdb4heh/pdb
PDB entry 4heh coloured by chain, front view.
PDB entry 4heh coloured by chain, side view.
PDB entry 4heh coloured by chain, top view.
Source organism: Cereibacter sphaeroides
Primary publication:
Redox and light control the heme-sensing activity of AppA.
Yin L, Dragnea V, Feldman G, Hammad LA, Karty JA, Dann CE, Bauer CE
mBio 4 e00563-13 (2013)
PMID: 23982072

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176042 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BLUF domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 216 amino acids
Theoretical weight: 22.76 KDa
Source organism: Cereibacter sphaeroides
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q53119 (Residues: 186-398; Coverage: 47%)
Gene name: appA
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 54.044Å b: 64.489Å c: 56.772Å
α: 90° β: 96.23° γ: 90°
R-values:
R R work R free
0.187 0.182 0.236
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Interdependence of tetrapyrrole metabolism, the generation of oxidative stress and the mitigative oxidative stress response.
Busch et al. (2015)
2 more

3 mentions without citation

Members of the PpaA/AerR Antirepressor Family Bind Cobalamin.
Vermeulen et al. (2015)
2 more