› 4hgl

X-ray diffraction
2.4Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195374 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Casein kinase I isoform gamma-3 Chain: A
Molecule details ›
Chain: A
Length: 330 amino acids
Theoretical weight: 38.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y6M4 (Residues: 34-362; Coverage: 74%)
Gene name: CSNK1G3
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand 0YO 1 x 0YO
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P3121
Unit cell:
a: 57.439Å b: 57.439Å c: 223.416Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.26 0.26 0.282
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Casein kinases as potential therapeutic targets.
Cozza et al. (2016)
2 more

1 mention without citation

The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis.
Knippschild et al. (2014)