› 4hv0

X-ray diffraction
2.6Å resolution

Structure and Function of AvtR, a Novel Transcriptional Regulator from a Hyperthermophilic Archaeal Lipothrixvirus

Released:
DOI: 10.2210/pdb4hv0/pdb
PDB entry 4hv0 coloured by chain, front view.
PDB entry 4hv0 coloured by chain, side view.
PDB entry 4hv0 coloured by chain, top view.
Source organism: Acidianus filamentous virus 6
Primary publication:
Structure and function of AvtR, a novel transcriptional regulator from a hyperthermophilic archaeal lipothrixvirus.
Peixeiro N, Keller J, Collinet B, Leulliot N, Campanacci V, Cortez D, Cambillau C, Nitta KR, Vincentelli R, Forterre P, Prangishvili D, Sezonov G, van Tilbeurgh H
J Virol 87 124-36 (2013)
PMID: 23055559

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108471 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribbon-helix-helix protein CopG domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 106 amino acids
Theoretical weight: 13.02 KDa
Source organism: Acidianus filamentous virus 6
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A7WKI3 (Residues: 1-100; Coverage: 100%)
Sequence domains: Ribbon-helix-helix protein, copG family
Structure domains: Met repressor-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 16 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 50.153Å b: 59.55Å c: 84.039Å
α: 90° β: 102.76° γ: 90°
R-values:
R R work R free
0.214 0.211 0.258
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

The wonderful world of archaeal viruses.
Prangishvili D. (2013)
4 more

3 mentions without citation

Structure and mechanisms of viral transcription factors in archaea.
Sheppard et al. (2017)
2 more