› 4hye

X-ray diffraction
1.7Å resolution

Crystal structure of a response regulator spr1814 from Streptococcus pneumoniae reveals unique interdomain contacts among NarL family proteins

Released:
DOI: 10.2210/pdb4hye/pdb
PDB entry 4hye coloured by chain, front view.
PDB entry 4hye coloured by chain, side view.
PDB entry 4hye coloured by chain, top view.
Source organism: Streptococcus pneumoniae R6
Primary publication:
Crystal structure of the response regulator spr1814 from Streptococcus pneumoniae reveals unique interdomain contacts among NarL family proteins.
Park AK, Moon JH, Oh JS, Lee KS, Chi YM
Biochem Biophys Res Commun 434 65-9 (2013)
PMID: 23545256

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184115 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Response regulator Chains: A, B
Molecule details ›
Chains: A, B
Length: 220 amino acids
Theoretical weight: 24.6 KDa
Source organism: Streptococcus pneumoniae R6
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8DNC2 (Residues: 1-199; Coverage: 100%)
Gene names: rr11, spr1814
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P212121
Unit cell:
a: 46.91Å b: 71.376Å c: 117.727Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.198 0.242
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation.
Trajtenberg et al. (2014)
5 more

3 mentions without citation

Molecular Mechanisms of Two-Component Signal Transduction.
Zschiedrich et al. (2016)
2 more