› › Structure analysis

HMG-CoA reductase from pseudomonas mevalonii complexed with dithio-HMG-coa

X-ray diffraction
1.5Å resolution
PDB entry 4i56 coloured by chain, front view.
PDB entry 4i56 coloured by chain, side view.
PDB entry 4i56 coloured by chain, top view.
Source organism: Pseudomonas mevalonii
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: 3-hydroxy-3-methylglutaryl-coenzyme A reductase
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 25470.29 Å2
Buried surface area: 10901.85 Å2
Dissociation area: 4,908.09 Å2
Dissociation energy (ΔGdiss): 78.61 kcal/mol
Dissociation entropy (TΔSdiss): 15.18 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-146717

Macromolecules

3-hydroxy-3-methylglutaryl-coenzyme A reductase
Chains: A, B
Length: 428 amino acids
Theoretical weight: 45.64 KDa
Source organism: Pseudomonas mevalonii
Expression system: Escherichia coli
UniProt:
  • Canonical: P13702 (Residues: 1-428; Coverage: 100%)
Gene name: mvaA
Pfam: Hydroxymethylglutaryl-coenzyme A reductase
InterPro:
CATH:
3-hydroxy-3-methylglutaryl-coenzyme A reductase in PDB entry 4i56, assembly 1, front view.
3-hydroxy-3-methylglutaryl-coenzyme A reductase in PDB entry 4i56, assembly 1, side view.
3-hydroxy-3-methylglutaryl-coenzyme A reductase in PDB entry 4i56, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links