Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
- Immunoglobulin C1-set
- MHC class II, beta chain, N-terminal
- Immunoglobulin/major histocompatibility complex, conserved site
- Immunoglobulin-like domain
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like fold
- MHC class II, alpha chain, N-terminal
- MHC class II, alpha/beta chain, N-terminal
1 more domain
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135340 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class II histocompatibility antigen, DR alpha chain
Molecule details ›
Chains: A, D
Length: 187 amino acids
Theoretical weight: 21.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 187 amino acids
Theoretical weight: 21.67 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P01903 (Residues: 27-213; Coverage: 82%)
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DRB1 beta chain
Molecule details ›
Chains: B, E
Length: 192 amino acids
Theoretical weight: 22.38 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Structure domains:
Length: 192 amino acids
Theoretical weight: 22.38 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P01911 (Residues: 31-222; Coverage: 81%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 23-ID-D
Spacegroup:
C2221
Expression system: Spodoptera frugiperda
