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Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog

Source organism: Bos taurus
Biochemical function: cAMP-dependent protein kinase regulator activity
Biological process: regulation of protein phosphorylation
Cellular component: cAMP-dependent protein kinase complex

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00027
Domain description: Cyclic nucleotide-binding domain
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
The deposited structure of PDB entry 4jv4 contains 2 copies of Pfam domain PF00027 (Cyclic nucleotide-binding domain) in cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR000595
Domain description: Cyclic nucleotide-binding domain
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
IPR018488
Domain description: Cyclic nucleotide-binding, conserved site
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
IPR018490
Domain description: Cyclic nucleotide-binding domain superfamily
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
IPR014710
Domain description: RmlC-like jelly roll fold
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
IPR012198
Domain description: cAMP-dependent protein kinase regulatory subunit
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed

Structure domain

CATH CATH domain
2.60.120.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
The deposited structure of PDB entry 4jv4 contains 2 copies of CATH domain 2.60.120.10 (Jelly Rolls) in cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed. Showing 2 copies in chain A.

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