› 4la1

X-ray diffraction
2.35Å resolution

Crystal structure of SjTGR (thioredoxin glutathione reductase from Schistosoma japonicumi)complex with FAD

Released:
DOI: 10.2210/pdb4la1/pdb
PDB entry 4la1 coloured by chain, front view.
PDB entry 4la1 coloured by chain, side view.
PDB entry 4la1 coloured by chain, top view.
Source organism: Schistosoma japonicum
Entry authors: Peng Y, Wu Q, Huang F, Chen J, Li X, Zhou X, Fan X

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-110235 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
thioredoxin-disulfide reductase Chains: A, B
Molecule details ›
Chains: A, B
Length: 602 amino acids
Theoretical weight: 65.83 KDa
Source organism: Schistosoma japonicum
Expression system: Escherichia coli
UniProt:
  • Canonical: B5THG7 (Residues: 1-596; Coverage: 100%)
Gene name: TGR
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand FAD 2 x FAD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P212121
Unit cell:
a: 84.185Å b: 86.47Å c: 183.164Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.171 0.234
Expression system: Escherichia coli

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