› 4lcb

X-ray diffraction
2.08Å resolution

Structure of Vps4 homolog from Acidianus hospitalis

Released:
DOI: 10.2210/pdb4lcb/pdb
PDB entry 4lcb coloured by chain, front view.
PDB entry 4lcb coloured by chain, side view.
PDB entry 4lcb coloured by chain, top view.
Source organism: Acidianus hospitalis W1
Primary publication:
The oligomeric state of the active Vps4 AAA ATPase.
Monroe N, Han H, Gonciarz MD, Eckert DM, Karren MA, Whitby FG, Sundquist WI, Hill CP
J Mol Biol 426 510-25 (2014)
PMID: 24161953

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123465 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell division protein CdvC, Vps4 Chain: A
Molecule details ›
Chain: A
Length: 367 amino acids
Theoretical weight: 42.25 KDa
Source organism: Acidianus hospitalis W1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: F4B4B0 (Residues: 1-365; Coverage: 100%)
Gene name: Ahos_1335
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P65
Unit cell:
a: 95.962Å b: 95.962Å c: 79.499Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.213 0.254
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery.
Christ et al. (2017)
11 more

1 mention without citation

The oligomeric state of the active Vps4 AAA ATPase.
Monroe et al. (2014)