› 4lp8

X-ray diffraction
2.46Å resolution

A Novel Open-State Crystal Structure of the Prokaryotic Inward Rectifier KirBac3.1

Released:
DOI: 10.2210/pdb4lp8/pdb
PDB entry 4lp8 coloured by chain, front view.
PDB entry 4lp8 coloured by chain, side view.
PDB entry 4lp8 coloured by chain, top view.
Source organism: Magnetospirillum magnetotacticum
Primary publication:
Control of KirBac3.1 potassium channel gating at the interface between cytoplasmic domains.
Zubcevic L, Bavro VN, Muniz JR, Schmidt MR, Wang S, De Zorzi R, Venien-Bryan C, Sansom MS, Nichols CG, Tucker SJ
J Biol Chem 289 143-51 (2014)
PMID: 24257749

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inward rectifier potassium channel Kirbac3.1 Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 33.88 KDa
Source organism: Magnetospirillum magnetotacticum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D9N164 (Residues: 1-295; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand PEG 1 x PEG
Ligand K 8 x K
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P4212
Unit cell:
a: 105.65Å b: 105.65Å c: 89.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.18 0.248
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Calcium channel gating.
Hering et al. (2018)
1 more

4 mentions without citation

Structure of potassium channels.
Kuang et al. (2015)
3 more