› 4mt2

X-ray diffraction
2Å resolution

COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE X-RAY CRYSTAL STRUCTURE OF RAT METALLOTHIONEIN-2

Released:
DOI: 10.2210/pdb4mt2/pdb
PDB entry 4mt2 coloured by chain, front view.
PDB entry 4mt2 coloured by chain, side view.
PDB entry 4mt2 coloured by chain, top view.
Source organism: Rattus rattus
Primary publication:
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Braun W, Vasák M, Robbins AH, Stout CD, Wagner G, Kägi JH, Wüthrich K
Proc Natl Acad Sci U S A 89 10124-8 (1992)
PMID: 1438200

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137604 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallothionein-2 Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 6.18 KDa
Source organism: Rattus rattus
Expression system: Not provided
UniProt:
  • Canonical: P04355 (Residues: 1-61; Coverage: 100%)
Gene name: Mt2
Sequence domains: Metallothionein
Structure domains: Metallothionein Isoform II

Ligands and Environments

3 bound ligands:
Ligand CD 5 x CD
Ligand ZN 2 x ZN
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 30.9Å b: 30.9Å c: 120.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 not available
Expression system: Not provided

Quick links

Citations

24 review citations

Roles of the metallothionein family of proteins in the central nervous system.
Hidalgo et al. (2001)
23 more

21 mentions without citation

Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets.
Chen et al. (2024)
20 more