› 4o2i

X-ray diffraction
2.2Å resolution

The crystal structure of non-LEE encoded type III effector C from Citrobacter rodentium

Released:
DOI: 10.2210/pdb4o2i/pdb
PDB entry 4o2i coloured by chain, front view.
PDB entry 4o2i coloured by chain, side view.
PDB entry 4o2i coloured by chain, top view.
Source organism: Citrobacter rodentium
Entry authors: Chang C, Xu X, Cui H, Savchenko A, Adkins J, Joachimiak A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180313 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-LEE encoded type III effector C Chains: A, B
Molecule details ›
Chains: A, B
Length: 324 amino acids
Theoretical weight: 36.7 KDa
Source organism: Citrobacter rodentium
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6RYA8 (Residues: 1-324; Coverage: 98%)
Gene name: nleC
Sequence domains: NFkB-p65-degrading zinc protease

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2221
Unit cell:
a: 73.937Å b: 89.356Å c: 205.416Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.168 0.237
Expression system: Escherichia coli

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