Function and Biology Details
Reaction catalysed:
(1a) a [histone H3]-N(6),N(6)-dimethyl-L-lysine(36) + 2-oxoglutarate + O(2) = a [histone H3]-N(6)-methyl-L-lysine(36) + succinate + formaldehyde + CO(2)
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Lysine-specific demethylase 2B (preferred)
PDBe Complex ID:
PDB-CPX-185550 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysine-specific demethylase 2B
Molecule details ›
Chains: A, B, C
Length: 118 amino acids
Theoretical weight: 13.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
Length: 118 amino acids
Theoretical weight: 13.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q8NHM5 (Residues: 607-723; Coverage: 9%)
Sequence domains:
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)
