› 4pf4

X-ray diffraction
1.13Å resolution

1.1A X-RAY STRUCTURE OF THE APO CATALYTIC DOMAIN OF DEATH-ASSOCIATED PROTEIN KINASE 1, aa 1-277

Released:
DOI: 10.2210/pdb4pf4/pdb
PDB entry 4pf4 coloured by chain, front view.
PDB entry 4pf4 coloured by chain, side view.
PDB entry 4pf4 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Temmerman K, Simon B, Wilmanns M

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death-associated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 31.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P53355 (Residues: 1-277; Coverage: 19%)
Gene names: DAPK, DAPK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

4 bound ligands:
Ligand SO4 4 x SO4
Ligand NA 2 x NA
Ligand GOL 6 x GOL
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 46.516Å b: 62.005Å c: 88.375Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.118 0.117 0.15
Expression system: Escherichia coli BL21

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