› 4qnd

X-ray diffraction
1.7Å resolution

Crystal structure of a SemiSWEET

Released:
DOI: 10.2210/pdb4qnd/pdb
PDB entry 4qnd coloured by chain, front view.
PDB entry 4qnd coloured by chain, side view.
PDB entry 4qnd coloured by chain, top view.
Source organism: Vibrio sp. N418
Primary publication:
Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Xu Y, Tao Y, Cheung LS, Fan C, Chen LQ, Xu S, Perry K, Frommer WB, Feng L
Nature 515 448-452 (2014)
PMID: 25186729

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123761 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sugar transporter SemiSWEET Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 11.12 KDa
Source organism: Vibrio sp. N418
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: F9RBV9 (Residues: 1-97; Coverage: 100%)
Gene name: VIBRN418_06191
Structure domains: Monooxygenase

Ligands and Environments

3 bound ligands:
Ligand MYS 2 x MYS
Ligand OLC 3 x OLC
Ligand PE5 1 x PE5
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I4122
Unit cell:
a: 58.236Å b: 58.236Å c: 172.923Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.198 0.206
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

26 review citations

Shared Molecular Mechanisms of Membrane Transporters.
Drew et al. (2016)
25 more

16 mentions without citation

GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters.
Deng et al. (2016)
15 more