› 4qyk

X-ray diffraction
3.5Å resolution

Crystal structure of a canine parvovirus variant

Released:
DOI: 10.2210/pdb4qyk/pdb
PDB entry 4qyk coloured by chain, front view.
PDB entry 4qyk coloured by chain, side view.
PDB entry 4qyk coloured by chain, top view.
Source organism: Feline panleukopenia virus
Primary publication:
Global displacement of canine parvovirus by a host-adapted variant: structural comparison between pandemic viruses with distinct host ranges.
Organtini LJ, Allison AB, Lukk T, Parrish CR, Hafenstein S
J Virol 89 1909-12 (2015)
PMID: 25410876

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161032 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP1 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d
Length: 584 amino acids
Theoretical weight: 64.75 KDa
Source organism: Feline panleukopenia virus
Expression system: Felis catus
UniProt:
  • Canonical: P90456 (Residues: 154-737; Coverage: 79%)
Sequence domains: Parvovirus coat protein VP2

Ligands and Environments

1 bound ligand:
Ligand MG 30 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P42212
Unit cell:
a: 453.1Å b: 453.1Å c: 319.02Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.237 0.18 0.221
Expression system: Felis catus

Quick links

Citations

2 review citations

Role of capsid proteins in parvoviruses infection.
Tu et al. (2015)
1 more

6 mentions without citation

Twenty-Five Years of Structural Parvovirology.
Mietzsch et al. (2019)
5 more