› 4rgh

X-ray diffraction
1.9Å resolution

Human DNA Damage-Inducible Protein: From Protein Chemistry and 3D Structure to Deciphering its Cellular Role

Released:
DOI: 10.2210/pdb4rgh/pdb
PDB entry 4rgh coloured by chain, front view.
PDB entry 4rgh coloured by chain, side view.
PDB entry 4rgh coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Brynda J, Grantz Saskova K

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein DDI1 homolog 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 169 amino acids
Theoretical weight: 19.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5TDH0 (Residues: 212-360; Coverage: 37%)
Gene name: DDI2
Sequence domains: Aspartyl protease
Structure domains: Acid Proteases

Ligands and Environments

1 bound ligand:
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21212
Unit cell:
a: 66.87Å b: 86.4Å c: 52.12Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.208 0.256
Expression system: Escherichia coli BL21(DE3)

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