Function and Biology Details
Reaction catalysed:
ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Serine-tRNA ligase, type1
- Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
- Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
- Aminoacyl-tRNA synthetase, class II
- Serine-tRNA ligase catalytic core domain
- Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm
- Serine-tRNA synthetase, type1, N-terminal
- Serine-tRNA synthetase, type1, N-terminal domain superfamily
- Selenocysteine transfer RNA
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Serine--tRNA ligase, cytoplasmic and RNA (preferred)
PDBe Complex ID:
PDB-CPX-155963 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Serine--tRNA ligase, cytoplasmic
Molecule details ›
Chains: A, B
Length: 522 amino acids
Theoretical weight: 59.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 522 amino acids
Theoretical weight: 59.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P49591 (Residues: 1-514; Coverage: 100%)
Sequence domains:
Structure domains:
