Function and Biology Details
Reaction catalysed:
SsDNA + n NTP = ssDNA/pppN(pN)(n-1) hybrid + (n-1) diphosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
DNA primase (preferred)
PDBe Complex ID:
PDB-CPX-155974 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA primase small subunit
Molecule details ›
Chains: A, C
Length: 420 amino acids
Theoretical weight: 49.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: DNA primase small subunit
Structure domains: DNA primase, PRIM domain
Length: 420 amino acids
Theoretical weight: 49.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P49642 (Residues: 1-420; Coverage: 100%)
Sequence domains: DNA primase small subunit
Structure domains: DNA primase, PRIM domain
DNA primase large subunit
Molecule details ›
Chains: B, D
Length: 509 amino acids
Theoretical weight: 58.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Eukaryotic and archaeal DNA primase, large subunit
Structure domains: Transcription Elongation Factor S-II; Chain A
Length: 509 amino acids
Theoretical weight: 58.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P49643 (Residues: 1-509; Coverage: 100%)
Sequence domains: Eukaryotic and archaeal DNA primase, large subunit
Structure domains: Transcription Elongation Factor S-II; Chain A
