Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Large T antigen and Importin subunit alpha (preferred)
PDBe Complex ID:
PDB-CPX-136539 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit alpha
Molecule details ›
Chain: B
Length: 495 amino acids
Theoretical weight: 53.6 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Length: 495 amino acids
Theoretical weight: 53.6 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9C2K9 (Residues: 75-548; Coverage: 87%)
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Large T antigen
Molecule details ›
Chains: A, C
Length: 8 amino acids
Theoretical weight: 985 Da
Source organism: Macaca mulatta polyomavirus 1
Expression system: Not provided
UniProt:
Length: 8 amino acids
Theoretical weight: 985 Da
Source organism: Macaca mulatta polyomavirus 1
Expression system: Not provided
UniProt:
- Canonical: P03070 (Residues: 125-132; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X25
Spacegroup:
P212121
Expression systems:
- Escherichia coli
- Not provided
