4s0u

X-ray diffraction
2.35Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-150836 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
NKG2-D type II integral membrane protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 14.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26718 (Residues: 90-215; Coverage: 58%)
Gene names: D12S2489E, KLRK1, NKG2D
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A
UL16-binding protein 6 Chain: C
Molecule details ›
Chain: C
Length: 175 amino acids
Theoretical weight: 20.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5VY80 (Residues: 29-203; Coverage: 79%)
Gene names: RAET1L, ULBP6
Sequence domains: Class I Histocompatibility antigen, domains alpha 1 and 2
Structure domains: MHC class I-like antigen recognition-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 82.3Å b: 80Å c: 73.2Å
α: 90° β: 106.5° γ: 90°
R-values:
R R work R free
0.241 0.238 0.286
Expression systems:
  • Escherichia coli BL21(DE3)
  • Escherichia coli