› 4s1x

X-ray diffraction
1.9Å resolution

Crystal structure of HA2-Del-L2seM, Central Coiled-Coil from Influenza Hemagglutinin HA2 without Heptad Repeat Stutter

Released:
DOI: 10.2210/pdb4s1x/pdb
PDB entry 4s1x coloured by chain, front view.
PDB entry 4s1x coloured by chain, side view.
PDB entry 4s1x coloured by chain, top view.
Source organism: unidentified influenza virus
Primary publication:
A switch from parallel to antiparallel strand orientation in a coiled-coil X-ray structure via two core hydrophobic mutations.
Malashkevich VN, Higgins CD, Almo SC, Lai JR
Biopolymers 104 178-85 (2015)
PMID: 25753192

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108786 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Truncated hemagglutinin Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 38 amino acids
Theoretical weight: 4.71 KDa
Source organism: unidentified influenza virus
Expression system: Not provided
UniProt:
  • Canonical: A8TXX2 (Residues: 22-60; Coverage: 43%)
Gene name: HA
Sequence domains: Haemagglutinin

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P21
Unit cell:
a: 34.45Å b: 98.523Å c: 34.553Å
α: 90° β: 89.96° γ: 90°
R-values:
R R work R free
0.21 0.208 0.246
Expression system: Not provided

Quick links

Citations

1 review citation

Catalysis and Electron Transfer in De Novo Designed Metalloproteins.
Koebke et al. (2022)
3 other articles

1 mention without citation

A switch from parallel to antiparallel strand orientation in a coiled-coil X-ray structure via two core hydrophobic mutations.
Malashkevich et al. (2015)