› 4tzj

X-ray diffraction
2.85Å resolution

Structure of C. elegans HIM-3 bound to HTP-3 closure motif-4

Released:
DOI: 10.2210/pdb4tzj/pdb
PDB entry 4tzj coloured by chain, front view.
PDB entry 4tzj coloured by chain, side view.
PDB entry 4tzj coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins.
Kim Y, Rosenberg SC, Kugel CL, Kostow N, Rog O, Davydov V, Su TY, Dernburg AF, Corbett KD
Dev Cell 31 487-502 (2014)
PMID: 25446517

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124494 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HORMA domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 293 amino acids
Theoretical weight: 33.39 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli
UniProt:
  • Canonical: G5EBG0 (Residues: 1-280; Coverage: 96%)
Gene names: CELE_ZK381.1, ZK381.1, him-3
Sequence domains: HORMA domain
Structure domains: HORMA domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: R32
Unit cell:
a: 161.791Å b: 161.791Å c: 110.545Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.18 0.178 0.23
Expression system: Escherichia coli

Quick links

Citations

18 review citations

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.
Musacchio A. (2015)
17 more

3 mentions without citation

Disassembly of the Shieldin Complex by TRIP13.
Sarangi et al. (2020)
2 more