› 4uft

Electron Microscopy
4.3Å resolution

Structure of the helical Measles virus nucleocapsid

Released:
DOI: 10.2210/pdb4uft/pdb
PDB entry 4uft coloured by chain, front view.
PDB entry 4uft coloured by chain, side view.
PDB entry 4uft coloured by chain, top view.
Source organisms:
Primary publication:
Structural virology. Near-atomic cryo-EM structure of the helical measles virus nucleocapsid.
Gutsche I, Desfosses A, Effantin G, Ling WL, Haupt M, Ruigrok RW, Sachse C, Schoehn G
Science 348 704-7 (2015)
PMID: 25883315
Related structures: EMD-2867

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero 78-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145151 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Nucleoprotein Chain: B
Molecule details ›
Chain: B
Length: 391 amino acids
Theoretical weight: 43.51 KDa
Source organism: Measles virus strain Halle
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P10050 (Residues: 1-391; Coverage: 75%)
Gene names: N, NP
Sequence domains: Paramyxovirus nucleocapsid protein
5'-R(*CP*CP*CP*CP*CP*CP)-3' Chain: R
Molecule details ›
Chain: R
Length: 6 nucleotides
Theoretical weight: 1.79 KDa
Source organism: Spodoptera frugiperda

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.3Å
Relevant EMDB volumes: EMD-2867
Expression system: Spodoptera frugiperda

Quick links

Citations

28 review citations

Towards a structural understanding of RNA synthesis by negative strand RNA viral polymerases.
Reguera et al. (2016)
27 more

16 mentions without citation

Structure and organization of paramyxovirus particles.
Cox et al. (2017)
15 more