Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146288 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bone morphogenetic protein 2
Molecule details ›
Chains: A, B
Length: 114 amino acids
Theoretical weight: 12.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 114 amino acids
Theoretical weight: 12.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P12643 (Residues: 283-396; Coverage: 31%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Repulsive guidance molecule A
Molecule details ›
Chain: C
Length: 106 amino acids
Theoretical weight: 11.63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Repulsive guidance molecule (RGM) N-terminus
Length: 106 amino acids
Theoretical weight: 11.63 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q96B86 (Residues: 46-139; Coverage: 23%)
Sequence domains: Repulsive guidance molecule (RGM) N-terminus
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I03
Spacegroup:
P3221
Expression systems:
- Escherichia coli BL21(DE3)
- Homo sapiens
